Dylan had clinic on Wednesday last week and needed both a blood and platelet transfusion, but his white blood cells and neutrophils were ok. We were actually scheduled for Thursday but a bruise on Dylan’s arm indicated that his platelets were dropping. Since then he has been fine. He is half way through his 3rdcycle of Accutane and so far he has had no break down in his skin or lips, his only side effect is a slight headache and some joint pain. Tomorrow we will check into clinic and see were his counts are at.
Dr Cheung is having a meeting with parents here at RMDH on Wednesday night. This is not a usual occurrence so he must be pretty excited about the 8H9 clinical trial. Dr Cheung is the head of the Neuroblastoma Team at MSKCC and he spends 99.9% of his time in the laboratory making new discoveries in Neuroblastoma research. Since I have been here (2 1/2 years) I have only ever had one consultation with him, the rest of the time you occasionally see him flashing by through the pediatric floor. The 8H9 is the 3F8 therapy that has been very successful with Neuroblastoma in the brain, it is actually injected directly into the brain. Recently from what I understand, he has just discovered a way to deliver the 8H9 to children with relapse Neuroblastoma in other areas apart from the brain. Nick is currently the first patient on the study and I will learn more about it after Wednesday’s conference. I have also heard that parents are flying in just for the occasion!